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Bile acid glucuronides are substrates for the multidrug resistance-associated protein 3 (MRP3/ABCC3), an efflux transporter located on the basolateral membrane of hepatocytes that transports bile acid glucuronides out of the liver for urinary excretion, e.g., bile acid detoxification

Dass Patienten mit Multiple Sklerose in der Vergangenheit mit einer verkrzten Lebenserwartung rechnen mussten, legt eine viel beachtete Bevlkerungsstudie aus der norwegischen Provinz Hordaland nahe, die eine Zeitspanne von fast 60 Jahren (1953 bis 2012) abdeckt