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La creciente prevalencia mundial de enfermedades metablicas como la diabetes, el sndrome metablico y las consecuencias relacionadas a largo plazo continan planteando un reto a los sistemas de salud (5)

ALS-associated mutant TDP-43 is known to be aberrantly localized in mitochondria, but suppressing its mitochondrial localization protects against neurotoxicity in TDP-43 A315T mice (Wang et al., 2016)