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Store unopened vials at -20C (freezer) and reconstituted solutions at 2-8C (refrigerator) for optimal stability and shelf life

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Jackson MJPS, Bolaos J, Bruckdorfer R, Carlssen H, Elliot RM, Flier J, Griffiths HR, Heales S, Holst B, Lorusso M, Lund E, Moskaug JO, Moser U, Di Paola M, Polidori MC, Signorile A, Stahl W, Via-Ribes J, Astley SB: Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function

In this Review, we highlight the latest advances in our understanding of the mechanisms of action of metformin and discuss potential emerging novel therapeutic uses