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Additionally, GHK-Cu modulates the activity of matrix metalloproteinase-13 (MMP-13), an enzyme that is overactive in degenerative joint diseases and contributes to cartilage degradation

Kim and Gladyshev, 2004

The longer isoform a full-length protein that is 44 kDa long (He et al., 2024)

Along these lines, in cardiovascular cells where SOD level is low and NQO1 level is high, induction of NQO1 has been shown to be correlated with enhancing superoxide scavenging action, while its suppression correlated with a decrease in superoxide scavenging activity [14]