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Both in vitro and in vivo treatment significantly inhibited TLR-4 and elucidated to the role of estrogen receptor 1 (ESR1)/ NLR family, pyrin domain-containing protein 3 (NLRP3)/CASP-1 signaling [118]

There was no remarkable difference in the peak shifts of the immobilized liposomes prepared by sonication for either 20 min or 40 min, thus, we decided to continue with the 20 min sonication method in the following liposome studies

These drugs were never designed for more than short-term use

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