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10.1016/0140-6736(93)90881-g Lancet 171 WangA.PadulaA.SirotaM.WoodruffT

33 In our data, ROS was weakly or not increased by Con A injection in the liver and spleen of WT mice

However, when CAR function is further inhibited by CINPA1 during sepsis, lethality is increased, which is associated with the further downregulation of these metabolic genes, increased systemic inflammation and greater organ damage