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Therapeutically, pharmacological inhibitors targeting NLRP3 (e.g., MCC950), caspase-1, or IL-1 signaling have shown promise in preclinical neurodegenerative models by reducing neuroinflammation and preserving neuronal function [116,117,118,119,120,121,122]

Berberine may enhance the lipid-lowering effects of statins, but if you're already on a statin, don't add it to your line-up without asking your clinician first

Although direct experimental evidence for MPO inhibition by SA remains limited, its structural features and reported biological activities support the plausibility of such interactions

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