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Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke

In the Chicken Embryo Model, concentrations of GA at or above 6 M (1.02 mg/kg) found to induce significant embryotoxic effects, characterized by the dissolution of cerebral blood, degeneration of adipose tissue in neck muscles, and developmental disorders

Clin Exp Immunol 167 , 261268, (2012)

Disruption of this microbial balance, known as gut dysbiosis, can alter gut-brain communication and has been associated with cognitive decline, with impairments in learning and memory