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High-resolution structural MRI and voxel-based morphology (VBM) analysis were adopted to study the brain GM volume differences between smokers and non-smokers, and to detect whether baseline GM differences were related to Varenicline treatment outcome in smokers

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"The chemistry of this is very interesting," says Neal Benowitz, professor of medicine at the University of California, San Francisco and a leader of the California Consortium on Thirdhand Smoke