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Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

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Surprisingly, multiple ALS-causative mutations in FUS/TLS increase FUS/TLS interaction with SMN, thereby affecting the normal function of SMN by both reducing Gem bodies and changing steady-state levels of some snRNAs in transgenic mouse tissues and patient fibroblasts expressing mutant FUS/TLS

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(2) it has good supporting function

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included six randomized control trials comparing CoQ10 with a placebo or used as an adjunct treatment [85]

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