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217 Astrocytes play an important role in maintaining extracellular K + homeostasis in the CNS, as well as H + , Cl - , and Ca 2+ homeostassis

[DOI] [PubMed] [Google Scholar] 48.Langlois JA, Rosen CJ, Visser M, et al

For instance, metformin mitigates testicular damage caused by diabetes by reducing apoptosis and inducing autophagy through the PK2/PKR/AKT/GSK3 signaling pathway [30]

Almeida M, Han L, Martin-Millan M, Plotkin LI, Stewart SA, Roberson PK, Kousteni S, OBrien CA, Bellido T, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC