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Read the full version in the August 2016 issue

Shelf Life: Use reconstituted solutions within 30 days of mixing to ensure compound stability

Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

Patients should disclose all current medications, including prescription drugs, over-the-counter medicines, herbal products, vitamins, and nutritional supplements