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Description

In astrocytes, glutamine (Gln), the major precursor of Glu, is synthesized via Gln synthetase and transferred to neurons, where it is converted back into Glu by phosphate-activated glutaminase, further entering mitochondrial pathways

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DEGs were identified using the DESeq2 R package, and results were visualized as a volcano plot using the ggplot2 R package ( Metabolic genes were defined based on a curated list 6,40

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doi: 10.1152/ajpregu.00428.2006 110 AfonsoRALauttWWSchaferJLegareDJOliveiraAGMacedoMP

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Talwar D et al

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