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10.5897/IJMMS.9000042 648

This molecule is synthesized biologically through the action of an inducible heme enzyme, nitric oxide synthase, which forms NO by the oxidation by dioxygen of the guanidino group of Arg, which gets converted to citrulline

10.1016/j.freeradbiomed.2013.08.174 37

However, as we get older, the levels of glutathione in our bodies decrease, which contributes to the aging process and leads to dull, sagging, and wrinkled skin