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Transfection of GES-1 cells with miRNA-143, miRNA-152, and miRNA-181 mimics significantly decreased mature miRNA expression accompanied by xCT mRNA, and protein expression was significantly suppressed (Figures 4A,B)

Nevertheless, when a person whose intestinal barrier has been compromised by trauma, acute inflammatory conditions such as pancreatitis, burns, or surgery, increased endotoxin concentrations are present in the circulation [42, 56, 57]

Diabetes 49(11):17511760

Interestingly, Rawls et al (2004) showed that genes involved in cholesterol metabolism and trafficking as well as in bile acid biosynthesis could be modulated by the microbiota in both mice and zebrafish