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At 68 weeks, the 12mg group achieved an average weight loss of 28.7%, which translates to an average of 71.2 pounds lost

However, several medicines and substances can reduce the absorption or levels of vitamin B12 , including metformin, proton pump inhibitors, colchicine, chloramphenicol, aminosalicylic acid, neomycin, and heavy alcohol use

In explaining such research findings, Pernicious Anemia Relief (PAR) notes that obesity may stem from the habits of individuals who have a B12 deficiency or their co-occurring conditions

You may benefit from more B12 if you experience: Constant fatigue or weakness Numbness or tingling in hands or feet Poor concentration Low mood or irritability Shortness of breath If these sound familiar, speak with a healthcare provider