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Tobacco use disorder Tobacco dependence severity, cessation legacy and serial mediation in aging China Most tobacco products, including e cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other addictive products, using a nicotine product builds tolerance, leading to more Substance Spotlight: Tobacco & Nicotine (Part 3) There is no completely risk free way to use tobacco or nicotine, but understanding the risks and ways to reduce harm can help people make
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