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Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization - an in vivo rat model

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doi: 10.1016/j.nbd.2011.09.008 Summary Keywords cuprizone-induced demyelination, remyelination, gut-brain axis, gut microbiota, intestinal innate and adaptative immunity, multiple sclerosis, neuroinflammation, gliosis Citation Ferreira C, Carvalho F, Vieira P, Alves A, Palavra F, Almeida J, Alves V, Coscueta E, Pereira PD, Pintado M, S H, Castelo-Branco M, Reis F and Viana S (2025) Intestinal mucosal alterations parallel central demyelination and remyelination: insights into the gut-brain axis in the cuprizone model of multiple sclerosis