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Antioxidants & Redox Signaling, 14(3), 469480

Dirty Genes is your roadmap to believing in better genetic health

Creb, another culprit for Tigar promoter activity and expression

Their results showed that the knockout of TIGAR gene further reduced mitochondrial membrane potential, increased mitochondrial ROS and the activation of caspase-3, and triggered mitochondria-mediated apoptosis of damaged neurons (Li et al., 2014)