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Gene expression levels of the TA during exposure to H 2 O 2 was also conducted to confirm this conclusion, and qRT-PCR identified GSH-related genes that were upregulated, including GST, TrxR, GR, CAT, GPX, TRX, GRX, and PRX, belonging to GSH-dependent reactions in the TA (Figure 6 and Supplementary Figure S3)

However, in subgrouping by location, the four posterior circulation trials exhibited a significantly higher RR of sICH in EVT patients (RR = 7.48, 95% CI: 2.2724.61) with significant heterogeneity across subgroups (p 60ml), severe coma (GCS 6 hours) versus early (6 hours) windows

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The IMS also contains a pathway for oxidative protein folding (Chacinska et al , 2009