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Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain

Following gut immune activation, activated immune cells and effector molecules such as cytokines [e.g., Interleukin-17 (IL-17), Tumor Necrosis Factor-alpha (TNF- )] can promote local inflammatory responses, alter the oral microecological environment, and either inhibit or promote the growth of specific microbial communities, playing a pivotal role in the regulation of oral microbiota (Nagao et al., 2022)

Inflammation induced ER stress affects absorptive intestinal epithelial cells function and integrity

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