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The evidence is mixed and weak

Key patient characteristics and outcomes are presented in Table 1

The role of oxidative stress in the COVID-19 disease may involve recognition of the viral S-protein by angiotensin converting enzyme-2 (ACE2) receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production (Kozlov et al., 2021)

If you are comparing the two medications and travel frequently or have unreliable refrigeration, semaglutide's longer room-temperature stability may be a practical advantage worth considering