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Manuel Ruiz-Pablos (research technician, medical student, and patient with ME/CFS) published hundreds of papers on how the immune system relates to important diseases, including ME/CFS and Long Covid

Glutathione S -transferase P1 expression in cancer patients may also be influenced by the presence of allelic variants GSTP1 Ile 105 Val (rs1695) and GSTP1 Ala 114 Val (rs1138272), with homozygote rare allele frequencies of approximately 12% and 2% in the Caucasian population, respectively (Zimniak et al, 1994

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These observations from early signaling involving the interplay of flavonoids and Nod factor production are a clear example of how a potential stress, flavonoids, induce a bacterial signal, Nod factor, that have become a key component for symbiotic interaction