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There are six main substance groups that cause damage to peripheral sensory and motor neurons, resulting in development of CIPN: the platinum-based antineoplastics (particularly oxaliplatin and cisplatin), the vinca alkaloids (particularly vincristine and vinblastine), the epothilones (ixabepilone), the taxanes (paclitaxel, docetaxel), the proteasome inhibitors (bortezomid) and immunomodulatory drugs (thalidomide)

The implications of neutrophil extracellular traps in the pathophysiology of atherosclerosis and atherothrombosis

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AppA activity was determined in a similar manner to that of PhoA except that the pH optima of the enzyme and absorbance maxima of the chromogenic product meant that a discontinuous assay had to be performed