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Description

Calcif Tissue Int

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Blocking NNMT preserves the NAD+ precursor pool (1.2-1.6x increase in intracellular NAD+), increases SAM availability for epigenetic methylation, and activates SIRT1/SIRT3 signaling

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BMC Med Genet 8:S15

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doi:10.1089/acm.2005.11.909

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