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To evaluate potential publication bias in the meta-analysis, the linear regression test for funnel plot asymmetry (Eggers test) was performed, with the standard error as the predictor and inverse variance as the weight, accounting for multiplicative residual heterogeneity ( 2 = 7.220)

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Some practitioners implement cycling to theoretically prevent receptor desensitization, provide physiological breaks, or manage costs, though evidence supporting these approaches is limited

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See examples of dosage in Table 2

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