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After activating the TLR signaling pathway, which leads to the induction of many genes that play a role in host defense, including inflammatory cytokines, chemokines, and antigen-presenting molecules (Kordjazy et al., 2018)

Although newer medications like crisaborole and dupilumab have shown effectiveness in treating AD, their high cost makes them inaccessible to most patients at present (211, 212)

We describe the molecular and structural basis for the recognition of ASXL1 and homologous ASXL2 and ASXL3 by the ET domain of BRD4 (BRD4 ET )

doi: 10.3389/fragi.2024.1495029 Received 11 September 2024 Accepted 13 November 2024 Published 26 November 2024 Volume 5 - 2024 Edited by Alexander Koliada, National Academy of Sciences of Ukraine (NAN Ukraine), Ukraine Reviewed by Carlos F