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Abstract Glutaredoxins are key players in cellular redox homoeostasis and exert a variety of essential functions ranging from glutathione-dependent catalysis to iron metabolism

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These advances, combined with the increase in using cellular therapies such as exosome-based therapies, promise not only to mitigate symptoms but literally reconstruct the very infrastructure of damaged brain tissue

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Although addition of NAC blocked the AUR/BSO- or AUR/ERA-stimulated increase in NOXA mRNA levels, -Toc partly reduced the increase in NOXA mRNA levels in AUR/ERA-treated, but not in AUR/BSO-treated cells (Figure 4b)

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