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[167] Duration of treatment represents another important consideration in melatonin therapy

doi:10.1016/j.envres.2022.114604 Chen H, Samet JM, Bromberg PA, Tong H

The expression of dopamine receptor D2 and transporter solute carrier family 6 member 3 (SLC6A3) in the penis was decreased, and the catechol-O-methyltransferase (COMT) was increased in the depression model rats (73)

This modification influences key processes such as glucose and lipid metabolism, cell signaling, transcriptional regulation, cellular stress, and hostpathogen interactions [11,12]