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The polygenic nature of breast cancer has been illuminated by the polygenic risk score computed based on multiple genome-wide association studies (GWAS), implicating over 180 single-nucleotide polymorphisms (64, 65)

Storage Instructions: Store in a cool, dark place out of reach of children Disclaimer: Food supplements should not be used as a substitute for a varied diet

doi: 10.1177/10781552231178686 15

In addition to affecting autophagy, the activation of the PI3K/Akt/mTOR signaling pathway in intestinal epithelial cells is also closely associated with the expression of tight junction proteins (Wang et al., 2015)