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The major mechanisms by which the drug is cleaved from the antibody include hydrolysis in the acidic pH of the lysosomes (hydrazones, acetals, and cis-aconitate-like amides), peptide cleavage by lysosomal enzymes (the cathepsins and other lysosomal enzymes), and reduction of disulfides

Understanding Dihexa Concentration and Reconstitution Math Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) arrives as lyophilized powder in vials labeled by total peptide mass

Researchers typically use a standard insulin syringe, which is small and has a very fine gauge needle (usually 29-31g)