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Secondary outcome measurements included reduction in body weight from baseline by at least 5% or 10% by week 26, changes in waist circumference, total cholesterol, HDL, LDL, VLDL, and triglycerides, and levels of different glycemic variables including HbA1C, fasting plasma glucose, fasting insulin, insulin resistance, and the functioning of beta-cells

Julius M, Lang CA, Gleiberman L, Harburg E, DiFranceisco W, Schork A

Whether you require surgical intervention or wish to stick to more conservative measures, you owe it to yourself to see if you might be a candidate for orthobiologics