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Description

Comparison of solution structural flexibility and zinc binding domains for insulin, proinsulin, and miniproinsulin

BaiKHaoEHuangCYueQWangD-HShiLet al

Initially, TMAO promotes foam cell formation through scavenger receptors in macrophages and downregulates main BA synthesizing enzymes cyp7a1 and cyp27a1, reducing intracellular BA levels and affecting hepatic CHO, BA production, and bile secretion, leading to hypercholesterolemia