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wherein the presence or increase in copy number, amount, and/or activity of at least one target listed in table 1 and/or the absence or decrease in copy number, amount, and/or activity of at least one target listed in table 2, relative to a control copy number, amount, and/or activity of the at least one target, indicates that the monocyte and/or macrophage can increase its inflammatory phenotype by modulating the at least one target