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Undoubtedly, the corticosteroid response is lower in patients with ACLF than those without ACLF, and further decreases with ACLF grades (126), which could be due to the fact that corticosteroids are more effective in patients at the preliver failure stage

Research interest in BPC-157 began with its effects on gastrointestinal healing, but studies quickly expanded to include tendons, ligaments, muscles, nerves, and joints

Data availability All genomes used are publicly available in the Unified Human Gastrointestinal Genome catalogue ( and the European Nucleotide Archive (see Supplementary Data 1 for list of accession codes and genome identifiers)