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191 Structurally, synthetic lipids usually contain three parts: (i) cationic or ionizable head groups, (ii) linker groups, and (iii) hydrophobic tails (Figure 2)

1 Introduction Diabetic ketoacidosis (DKA) represents a critical and potentially life-threatening acute complication observed in individuals diagnosed with diabetes (Pasquel et al., 2021)

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Gene set enrichment analysis (GSEA) was performed with 1000 permutations to identify enriched biological functions and activated pathways from the molecular signatures database (MSigDB), which included hallmark gene sets, positional gene sets, curated gene sets, motif gene sets, computational gene sets, GO gene sets, oncogenic gene sets, and immunologic gene sets