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This imbalance can trigger the production of an array of ROS, such as NO, O 2 , H 2 O 2 , etc., which play important roles in the pathophysiological processes that drive gout inflammation [6]

Intracellular NADPH measurements 4T1 cells were incubated in a six-well culture plate (3 10 5 cells/well) for 24 h, followed by incubation with different formulations for 24 h