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Inhibitors of FASN (such as TVB-2640, which has advanced to clinical trials) and acetyl-CoA carboxylase (ACC) inhibitors have shown preclinical efficacy in reducing tumor growth and overcoming resistance to targeted therapies

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2019 doi: 10.1016/j.freeradbiomed.2018.08.038

Along with its angiogenic and cytoprotective enzyme functions, HO-1 performed crucial biological activities, making it highly significant in the wound healing process