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In the novelty suppressed feeding test, PE-22-28 reduced latency to feed, an effect that requires chronic antidepressant treatment with SSRIs but occurred after acute PE-22-28 administration

(2014, J Pharmacol Exp Ther), were formally retracted in April 2025 following a 2021 Notice of Concern regarding data integrity

Published research has identified several key pathways: Angiogenesis promotion: BPC-157 stimulates the formation of new blood vessels, enhancing blood supply to injured tissues