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Regulation of Met metabolism in the liver In the liver, when the consumption of Met exceeds its average dietary intake, de novo synthesis of Met occurs via the transfer of a methyl group from methylene-THF first by methylene-THF reductase (MTHFR) and then by Met synthase (MS) to Hcy to form Met to make up the difference (Figure 2)

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The phase-specific codes When the chart documents which phase of the swallow is affected, you move off R13.10 to a specific code: R13.11: Oral phase