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type 1 diabetes, rheumatoid arthritis) Emotional or physical stress, such as stressful events or serious illness, may act as triggers Pregnancy and recent childbirth Smoking The overall prevalence of hyperthyroidism in the US is around 1.2% with an incidence of 20/100,000 to 50/100,000

Beta-oxidation: the burning of fats Once inside the mitochondria, fatty acids are released and enter a process called beta-oxidation : they are progressively "broken down" into smaller units (acetyl-CoA), which then fuel the Krebs cycle and the respiratory chain to produce ATP (the cell's energy currency)

The early manifestation of diabetic cardiomyopathy is isolated diastolic dysfunction, which transitions to systolic dysfunction as the disease progresses

AAV-mediated base-editing therapy ameliorates the disease phenotypes in a mouse model of retinitis pigmentosa