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Experimental and real-world studies have directly evaluated the effects of JUUL2 products on cigarette smoking behavior, specifically switching away from cigarettes, subjective responses, patterns of use, as well as abuse liability and dependence relative to combustible cigarettes and other ENDS products

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When inhaled, CO binds with hemoglobin in the lungs, decreasing the amount of red blood cells necessary to transport oxygen throughout the body

However, youth experimentation with vaping is also increasing