glutathione and napqi Most people don't realise this Paracetamol breaks down into a toxic compound called NAPQI. Your liver neutralizes it using (your body's defense shield). But when you take it too often — Mitochondrial damage produced by N‐acetyl‐p‐benzoquinone
Mitochondrial damage produced by Nacetylpbenzoquinone imine (NAPQI). Download Scientific Diagram 5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. Hepsin as a potential therapeutic target for alleviating acetaminophen induced hepatotoxicity via gap junction regulation and oxidative stress modulation Cell Biology and Toxicology Springer Nature Link Full article: Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease
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