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Further, its anti-asthma effects were also improved, evidence by improved asthma-associated inflammation, including eosinophil production, OVA-specific IgE, IL-4, IL-5, and IFN- at 10 mg/kg compared to the group that received 20 mg/kg of free isoliquiritigenin [116]

It is also important to highlight the distinct affinities that histamine exhibits for these receptors

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This integrated understanding underscores the importance of considering both macroscopic and microscopic factors in managing ACL health and developing comprehensive strategies for injury prevention and rehabilitation (Table 5)