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Balance protection (avoiding re-injury) with appropriate activity (promoting healing)

Rintatolimod: toll-like receptor 3 (TLR3) agonist for ME/CFS therapy By activating TLR3, rintatolimod triggers a type I interferon-mediated antiviral response, which upregulates effector proteins such as 2-5 oligoadenylate synthetase and protein kinase R to degrade viral ribonucleic acid (RNA) and inhibit translation, collectively enhancing the hosts antiviral defense

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Levels decline with age and stress, which is why medically supervised supplementation can be beneficial for some patients