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MS spectrum shows the presence of a high abundance molecular ion (Retention time = 9.153 min) with m/z 279.0796 (M+H) + (557.1497 (2M+H) + ) which corresponds precisely to a predicted molecular formula of C13 H14 N2 O3 S - a putative monothiol form of gliotoxin

The integration of gene therapy, targeted delivery vehicles, and immune-based modulation offers a sophisticated framework to counteract neuronal loss and functional decline in neurodegenerative disorders

For statistical decision criteria, a significance level of 0.05 was adopted

Although clinical translation remains in its early stages, the gut-brain axis represents a promising, non-invasive, and systems-level target for neuroprotection