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Yes, especially when the irregularity is linked to insulin resistance, PCOS, stress or nutrient gaps

doi: 10.1016/B978-0-12-800173-8.00003-9 300 DailyJWYangMParkS

According to a 2018 review published in Advanced Food and Nutrition Research, low B6 may increase the risk of inflammation, obesity, chronic health issues, and carcinogenesis ( 19 )