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Worthington, A

Research suggests that B vitamins may help reduce certain menopausal symptoms by supporting nervous system function, protecting against cognitive decline, and promoting a healthy balance of gut bacteria

However, some men, particularly those with higher body fat and greater aromatase activity, can develop estradiol levels high enough to cause symptoms: reduced libido, mood instability, or gynecomastia

The monoclonal antibody Mab5G9, which blocks TF-VIIa-mediated activation of PAR-2 and disrupts the interaction of TF with integrins, has also shown antineoplastic activity in breast cancer preclinical models [121]