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hence, addition of intrinsic factor in the second step results in an increase in vitamin B 12 absorption (over the baseline established in the first)

Some recent results with relatively cost-effective NIR instruments show that there is an opportunity to use a handheld near-infrared device (NIR, 13502550 nm) for near-real-time SOC measurements (Kalopesa et al., 2025)

The Gray Zone, and the Test That Resolves It Experts advise that when serum B12 lands between 150 and 399 pg/mL, methylmalonic acid should be measured to help confirm the diagnosis