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This highlights the extensive systemic influence of bile acids, affecting a spectrum of physiological and pathological conditions (284)

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96 MorrisD.KhurasanyM.NguyenT.KimJ.GuilfordF.MehtaR.et al (2013)

When ROS accumulation exceeds cellular detoxification capacity, oxidative damage to lipids, proteins, and nucleic acids occurs, potentially culminating in severe photoinhibition and the activation of programmed cell death pathways